Villanova vs. Oklahoma prediction, odds, line: 2022 college basketball picks, Dec. 3 best bets by proven model

The Oklahoma Sooners look to keep rolling on Saturday when they visit Philadelphia to take on the Villanova Wildcats in a 2022 Big East-Big 12 Battle men’s college basketball game. The Sooners (6-1) have won six straight since a one-point loss in their opener. They come off a 59-55 victory against Ole Miss at the ESPN Events Invitational last Sunday in Kissimmee, Fla. The Rebels entered that game unbeaten. The Wildcats (2-5) are struggling in their first season after the retirement of longtime coach Jay Wright. They have lost four straight, most recently a 74-67 setback to Oregon at the Phil Knight Invitational in Portland, Ore. The teams have met twice in their history, both in the 2015-16. The Sooners won the regular-season meeting 78-55 before the Wildcats demolished OU 95-51 in the Final Four on their way to the national title.    

Tip-off at the Wells Fargo Center is set for 12:30 p.m. ET. The Villanova are a 2.5-point favorite in the latest Oklahoma vs. Villanova odds at Caesars Sportsbook, while the over/under for total points scored is set at 125. Before you make any Villanova vs. Oklahoma picks, be sure you check out the college basketball predictions and betting advice from the SportsLine Projection Model.

Saturday’s game can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan.

Sign up now with promo code ALLYEAR to get 50% off one year of the Essential or Premium plan at Paramount+ (expires 12/31). A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, NFL on CBS and countless movies and shows. Get it all for 50% for a year with promo code ALLYEAR when you sign up right here.

The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its…

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