Spurs vs. Grizzlies odds, score prediction, start time: 2025 NBA picks, Jan. 17 best bets by proven model

The Memphis Grizzlies will look to win their second game in three days over the San Antonio Spurs when they meet in a key Southwest Division matchup on Friday night. Memphis defeated San Antonio 129-115 on Wednesday. The Grizzlies (26-15), who have won three of five, are 11-10 on the road this season. The Spurs (19-20), who have lost four of five, are 12-9 on their home court in 2024-25.

Tipoff from Frost Bank Center in San Antonio is set for 9:30 p.m. ET. San Antonio leads the all-time regular-season series 75-40, but Memphis has won 14 of the past 15 matchups. The Grizzlies are 2-point favorites in the latest Grizzlies vs. Spurs odds from SportsLine consensus, while the over/under for total points scored is 239. Before making any Spurs vs. Grizzlies picks, you’ll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 13 of the 2024-25 NBA season on a sizzling 135-97 roll on all top-rated NBA picks dating back to last season, returning well over $3,000. Anyone following at sportsbooks and on betting apps could have seen huge returns.    

Now, the model has set its sights on Grizzlies vs. Spurs and just locked in its picks and NBA predictions. You can head to SportsLine now to see its picks. Here are several NBA betting lines for Spurs vs. Grizzlies:

Grizzlies vs. Spurs spread: Memphis -2 Grizzlies vs. Spurs over/under: 239 points   Grizzlies vs. Spurs money line: Memphis -132, San Antonio +110MEM: The Grizzlies have covered the spread in 50 of their last 81 games (+15.90 units) SA: The Spurs have hit the money line in 30 of their last 62 games (+23.80 units)     
Grizzlies vs. Spurs picks: See picks at SportsLineGrizzlies vs. Spurs streaming: FuboTV (Try for free)

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