Lakers vs. Timberwolves odds, prediction, time: 2025 NBA playoff picks, Game 1 best bets from proven model

When the Lakers made the blockbuster trade to acquire Luka Doncic at the expense of Anthony Davis, it was largely motivated by pairing Doncic and LeBron James together in the postseason. We’ll see that duo for the first time in the 2025 NBA playoffs when the Los Angeles Lakers host the Minnesota Timberwolves on Saturday in Game 1 of their Western Conference first-round series. The Lakers went 50-32 overall, including 31-10 at home, this season. The Timberwolves went 49-33, including 22-19 on the road, this year. The Lakers and Timberwolves split their four matchups this season, with the home team winning each time. Los Angeles defeated Minnesota, 111-102, on Feb. 27 in their only meeting in the James-Doncic era.

Tipoff is set for 8:30 p.m. ET from Crypto.com Arena in Los Angeles. The Lakers are favored by 4 points in the latest Timberwolves vs. Lakers odds on FanDuel Sportsbook, while the over/under for total points scored is 216.5. Before making any Lakers vs. Timberwolves picks for the 2025 NBA playoffs, you’ll want to see the NBA predictions from the advanced computer model at SportsLine. 

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the 2025 NBA playoffs on a sizzling 156-115 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Los Angeles vs. Minnesota. You can head to SportsLine to see its picks. Here are several NBA betting lines for Timberwolves vs. Lakers:

Lakers vs. Timberwolves spread: Lakers -4 on FanDuelLakers vs. Timberwolves over/under: 216.5 pointsLakers vs. Timberwolves money line: Lakers -184, Timberwolves +154MIN: The Timberwolves went 9-5 against the spread (ATS) as an away underdog this seasonLAL: The Lakers went 27-14 ATS at home this season
Lakers vs. Timberwolves picks: See picks at…..

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